Abstract
JTC-3 cells were grown in YLE-media containing thiamine disulfide (TDS) and O-benzoylthiamine disulfide (BTDS) at high concentrations equivalent to 20 to 50 μg per ml of thiamine hydrochloride. The effects of these compounds on the cell growth and the susceptibility of the cell to Poliovirus Type I were studied. As a result, it was recognized that BTDS at high concentration as 50 μg per ml had slight inhibitory effect on the cell growth. On the other hand, TDS showed no such effect on the cell growth. On the viral growth both TDS and BTDS had no effect.
