Abstract
Electroretinogram (ERG) and microscopic structure of retina were investigated in both cases of riboflavin deficient and recovered rats. In the liver of riboflavin deficient rat, the content of total riboflavin became about 40 per cent of nomal rat by six weeks feeding and succinic acid dehydrogenase activities were less in every layers of retina than those of normal ones. A marked decrease of succinic acid dehydrogenase activity was found in both layers of bacillary and outerlimiting membranes. The b wave of ERG showed about 35 per cent decrease and ratio of b and a wave became below than one half in the riboflavin deficient rat in comparison with that of normal one, and the difference of two groups disappeared after the administration of riboflavin to riboflavin deficient group accompanied by normalization of total riboflavin content of liver.
