METABOLIC RELATION BETWEEN NUCLEOSIDES AND VITAMINS : (XIII) METABOLIC ACTIVITIES OF INOSINE ON THE INCORPORATION OF RIBOFLAVIN INTO RAT LIVER XANTHINE OXIDASE SYSTEM

Abstract

The metabolic activity of inosine on the incorporation of riboflavin into rat liver xanthine oxidase system was studied. On oral administration of inosine in rats, statistical significance was scarcely observed in the growth promoting effect, but it was found that the incorporation of riboflavin into rat liver is markedly accelerated. Further, the increases of FAD and FMN in liver tissue were always demonstrated.