Abstract
The author at first divided the rats into 2 groups, one a thiamine deficient group, giving the normal basal diet containing 20% casein and the other thiamine-protein deficient groups, giving the low protein diet with 5% casein. The growth in low protein group stopped after about 5 days, and in the third week, body weight was lowered almost to the initial one. However, the animals did not show any remakable thiamine deficient symptom, as marked neuroparalysis. Most of the rats died earlier than the adequate protein group. In spite of thiamine administration, body weight and appetite in low protein group did not increase. Effects of thiamine administration was not recognized for hypoprotein-thiamine-deficient rats.
