Abstract
Experimental studies of α-tocopherylnicotinate on the cooling-rewarming test were done for 30 human subjects by measurement of the skin temperature on the back of hands and finger tip. It was found that α-tocopherylnicotinate (600mg daily for 6 days) had the restoration of the mean rewarming time, especially in the constrictor type. Discussing the results, it was concluded that α-tocopherylnicotinate had the persistent and strong accelerating effects on the skin-microcirculation and its reserve strength, especially on the arterioles region.