Abstract
Kymographic studies were performed by Magnus method, using isolated segments of rat small intestine under well-controlled experimental condition. Excellent activities on intestinal movement was recognized after administration of various thiamine derivatives in Tyrode solution, such as thiamine-HCl (24μg/ml), thiamine-HNO_3 (24μg/ml), BTMP (15μg/ml), TPD (24μg/ml), BTDS (24μg/ml), TTFD (15μg/ml), thiamine-NDS (24μg/ml), DBT (15μg/ml) and iBuTDS (24μg/ml). No activity was observed in the case of Cl^- or NO_3^- or Tyrode solution.
