STUDIES ON THE CLINICAL EFFECT OF HOMOPANTOTHENIC ACID FOR CHILDRENS WITH MENTAL AND PHYSICAL DISORDERS

Abstract

It has been reported that homopantothenic acid (HOPA) which is obtained by the substitution of β-alanine group of pantothenic acid for γ-aminobutyric acid can easily pass through the blood brain barrier and exerts good effects on diseases of the brain. In the present clinical trial of HOPA therapy for 26 retarded children, it was also demonstrated that the electroence-phalogram was apparently improved and intelligence quotient was increased higher in HOPA-treated group than in the control group when tested "Analytical developmental examination method", designed by Enjoji.