Abstract
O-Acylthiamine esterase activities in the blood of in-patients of liver cirrhosis and chronic hepatitis were compared with that of healthy subjects. OBT esterase activities (expressed by an amount of thiamine produced per 100ml blood for 10 minutes) ranged from 11.8 to 23.8mg in the patients (9 cases) and from 17.4 to 31.2mg in healthy man (10 cases). OBuT esterase activities ranged from 147 to 239mg and from 126 to 256mg, respectively, in the patients and the normal subjects. It was concluded that there was no practically significant difference in the acylthiamine metabolizing ability between them.
