Abstract
In order to investigate the influence of large amounts of thiamine and thiamine propyldisulfide on the function of human brain, especially those of mental defectives, these compounds of 3mg/kg body weight were given intravenously to 16 children (9 of thiamine group and 7 of thiamine propyldisulfide group) with various types of mental deficiency, and electroencephalographic effects were studied before and after the injection. The results are briefly summarized as follows : 1) The frequency analysis of waking occipital EEG was done by means of an automatic frequency analyzer. As a result, no difference between before and after the injection was noted in each group. 2) The mean visual evoked potential of waking occipital EEG was recorded by means of a medical data processing computer, and peak latency periods were compared between before and after the injection. As a result, no difference was noted in each group.
