Abstract
In vivo experiments were carried out in detail on the reduction and the uptake of TPD by the blood and the following results were obtained. 1) There was a limit to the reduction and the uptake of TPD by the blood. The maximum reduction occured in the supernatant of the suspension with 0.5ml of human blood cells was about 200μg and the maximum uptake into the blood cells was about 400μg. The maximum reduction by 0.5ml of plasma was about 70μg. 2) The SH radical in the blood cells played a major role in reduction of TPD and this action was markedly suppressed by the addition of PCMB. 3) The reduction of TPD by the blood cells increased markedly by the co-existence of plasma when the blood cells were intact.
