Abstract
^<14>CH_3-Methylmethionine sulfonium iodide was administered on mice orally or intravenously, and its distribution in body was detected by autoradiographical technique. In the mucosa of digestive tract and liver, high density of radioactivity was detected. In the gastric and intestinal mucosa, the radioactivity was highest 4 hours after the administration. A small radioactivity was found in kidney and adrenal gland. These results agreed with the fact that methylmethionine sulfonium halide was capable to be the methyl-donor to both methylhistamine in gastric mucosa and lecithin in liver.
