Abstract
The clinical effects of vitamin E were investigated in 7 cases (3 adolescents and 4 adults) of purpura due to vascular defects caused bv infection, drugs or unknown etiologies. In this study, marked clinical improvements following the oral administration of vitamin E (400 to 600mg of α-tocopherol nicotinate per day) were observed in all cases. Six out of 7 cases showed remarkable improvements of petechiae following the vitamin E therapy alone. Complete disappearance of petechiae was observed following the administration of vitamin E for 5 days in 2 cases, 14 days in 4 cases and 21 days in 1 dase, along with the improvements of other clinical sym ptoms . (Receiaed May 24,1972)
