Abstract
The effects of riboflavin derivatives on the common carotid, femoral, renal, great auricular, coronary, and mesenteric arteries were studied in dogs anesthetized with pentobarbital. 1) FMN exerted no appreciable effects on any of the blood vessels tested. 2) FAD markedly constricted the renal artery, while it markedly dilated the common carotid, femoral, and coronary arteries. FAD also slightly dilated the great auricular and cranial mesenteric arteries. 3) DNRP dilated the great auricular, coronary, and cranial mesenteric arteries, while it constricted the renal artery. The degree of the renal artery constriction, however, was smaller than that produced by FAD. DNRP little affected the common carotid and femoral arteries. 4) NiA dilated the great auricular artery, but did not influence other blood vessels tested.
