Abstract
The effects of riboflavin (B_2), inosine (HxR) and some dietary conditions on xanthine dehydrogenase (XDH) activity in chick liver were studied by various combinations of these factors. Three kinds of diet, casein diet, gluten diet and B_2 free diet, were provided. The results were summarized as follows. (1) The XDH activity always increased by oral administration of HxR in every experiment. FAD content of liver also increased by administration of HxR. (2) The XDH activity in case of casein diet was slightly high when compared with gluten diet. (3) In case of B_2-deficiency, the administration of B_2 on the increase of the XDH activity was significantly effective, but the increase in amount of B_2 administration was no effect. (4) The administration of puromycin inhibited the effect of HxR on the increase of the XDH activity.