Abstract
Effects of intraperitoneal injection of reserpine on the levels of B_6 vitamers in mouse brain were examined. Injection of reserpine alone resulted in higher level of pyridoxal phosphate (PALP) and in lower level of pyridoxal (PAL), but did not influence on the levels of other vitamers. Intramuscular injection of pyridoxine (PIN) or pyridoxamine (PAM) after the injection of reserpine resulted in higher level of pyridoxine phosphate (PINP) or pyridoxamine phosphate (PAMP), respectively, but did not elevate to higher level of PALP than that of reserpine alone. Injection of PAL after the reserpine injection resulted rather in a decrease of PALP. Injection of PIN, PAL or PAM alone resulted in an unexpected decrease of PALP, though PIN and PAM elevated slightly the levels of PINP and PAMP, respectively.
