Abstract
The effect of ascorbate 2-sulfate (AsS) administration on AsS sulfohydrolase activity in guinea pig liver was studied. Guinea pigs fed on ascorbic acid (AsS) deficient diet were derived into six experimental groups - no AsA, 10mg AsS, 0.5mg AsA, 0.5mg AsA+10mg AsS, 2.0mg AsA and 2.0mg AsA +10mg AsS. After the feeding test for 14 days, the appearance of the generally accepted symptoms of scurvy was observed in the no AsA supplemented group and the 10 mg AsS supplemented group, indicating that AsS had no antiscorbutic activity in guinea pig. Also, no increase in the activities of AsS sulfohydrolase and arylsulfatase from guinea pig liver was observed in AsS administration.
