Abstract
Investigations on the thiamine concentrations in blood and urine of patients with congestive heart failure, compensated heart failure and other heart diseases without edema were conducted. When thiamine was administered, the thiamine concentrations in blood and urine were normal in the patients with heart failure. But without giving the thiamine, the concentrations were considerably lower as compared with the normal levels. They appear therefore to suffer from thiamine deficiency. The rate of thiamine excretion in the above patients was always low even when administered with vitamin. No thiamine deficiency was rocognized in compensated heart failures. Thiamine deficiency was also found in patients with severe other diseases, but in most of them hydremia was found contrary to the patients with heart failure.
