Abstract
Manganese (Mn) is an element used widely as the industrial raw material, and also is one of the essential trace elements for plants and animals. In recent years, the situation to administer the preparation of trace elements including manganese to prevent Mn deficiency has increased with the spread of total parenteral nutrition in the clinical field. Therefore, the knowledge of Mn as a nutrient is required in the clinical field. In this review, based on the recent findings, we outline the disposition, deficiency, excess, and nutritional assessment of Mn, and also introduce the current uses of Mn.