Abstract
Effects of 15 ascorbic acid derivatives on phage J1 of Lactobacillus casei were investigated in relation to the phage control in lactic fermentation. 5,6-O-isopropylidene-AsA, 2-O-(7,H-dodecafluoroheptanoyl)-AsA, 2-O-benzoyl-AsA, 2,6-di-O-benzoyl-AsA, 6-O-(7,H-dodecafluoroheptanoyl)-AsA, 6-bromo-6-deoxy-AsA, 5,6-dideoxy-O-glycero-hex-2,3:5,6-dienone-1,4-lactone and 6-O-phenyl-AsA exhibited little or no effect on the phage growth. 6-O-octanoyl-AsA partially inhibited the phage growth. 2-O-octanoyl-AsA and 2,3-bis-O-(1,1,2,3,3,3-hexafluoropropyl)-AsA completely inhibited the phage growth at the concentration which allowed bacterial growth, but differences in both concentrations were not so large. 2,6-bis-O- octanoyl-AsA, 2,6-bis-O-perfluorooctanoyl-AsA and 2,3-di-O-octanoyl-5,6-O-isopropylidene-AsA completely inhibited the phage growth at the concentration which inhibited completely bacterial growth. 2,3-bis-O-(7,H-dodecafluoroheptanoyl)-AsA exhibited little or no effect on the phage growth at the concentration which inhibited bacterial growth..
