特集「2019年日本表面真空学会学術講演会特集号Ⅱ」
グラフェン電界効果トランジスタを基盤としたバイオセンサ
2020 年 63 巻 7 号 p. 358-363
詳細
2020 年 63 巻 7 号 p. 358-363
Since ion-sensitive field effect transistors (ISFETs) have been developed in 1970, much attention has been focused on FET-based biosensors. In particular, graphene is one of the promising candidates for FET-based biosensors owing to their high electron/hole mobilities and unique 2D nature. Herein, we report specific detection of biomolecules using sialylglycopeptide-modified graphene FET (G-FET) biosensors. In addition, we also present state-space models (SSMs) to analyze time-series data of G-FET biosensors. This computational approach helps to separate the response against target biomolecules from the baseline drifted data. G-FET biosensors open the door to a more versatile sensing platform for biomolecules and biological functions.
