2016 Volume 32 Pages 39-40
The structure of the drug-drug multi-component crystal of acedoben–dimepranol (2:1) was determined by single-crystal X-ray crystallography. The compound crystallizes in a monoclinic system with space group P21/n resulting in the following unit cell: a = 7.78174(14)Å, b = 9.71395(18)Å, c = 63.5236(12)Å, β = 92.4271(7)°, Z = 4, V = 4797.53(15)Å3. The final values were R1 = 0.0443 and wR2 = 0.1241. Two acedoben molecules share a hydrogen atom between the COOH and COO– groups forming a mono cationic dimer unit. A counter charge is on NH+ of the dimepranol molecule.
