Studies on Pharmacological Activities of D-Cysteinolic Acid

Abstract

D-Cysteinolic acid (2-L-amino-3-hydroxy-1-propane sulfonic acid) isolated from sardine Sardinops melanostica was tested for pharmacological activities along with taurine. It inhibited the aggregation of rat platelet induced by collagen, thrombin and ADP, more effectively than taurine. However, it was less effective than taurine on the stability of rat erythrocyte membrane and inhibitory activity of gastric juice secretion in pylorus-ligated rat, and not effective on the blood pressure of carotid artery in spontaneously hypertensive rat.