A Novel Carbon-Carbon Bond Forming Reaction by Means of Sulfur-Ylide Rearrangement and Its Application to the Synthesis of Physiologically Active Compounds

Abstract

A novel carbon-carbon bond forming reaction has been developed by employing the rearrangement of sulfur ylides, easily derived by the preferential participation of carbene or carbenoid with the divalent sulfur, as a key step. This synthetic strategy has successfully been applied to the synthesis of physiologically active compounds.