Study on Alpiniae Fructus. I. Pharmacological Evidence of Efficacy of Alpiniae Fructus on Ancient Herbal Literature

Abstract

Pharmacological effects on anti-diuresis, anti-ulceration, anti-dementia and learning function of 50% ethanolic extract (AO-ext) from Alpiniae Fructus (fruit of Alpinia oxyphylla) removed seedvessel were investigated in order to prove the evidence of the efficacy of Alpiniae Fructus on the ancient herbal literature. AO-ext showed the effects of anti-diuresis, anti-ulceration, anti-dementia and on increase in the learning function in animals. And also, AO-ext exhibited the increasing effect on the serum 11-hydroxycorticosteroid (11-OHCS) level in the above-described experimental animals and in intact and hypophysectomized rats.