Abstract
Novel quinoxaline 1, 4-dioxide derivatives were synthesized from benzofuroxans and the enolic form of 1, 3-diketones or 3-oxoalkanoic esters or 3-oxoalkanamides or butanedioic esters catalyzed by silica gel or molecular sieves and their antibacterial activities were evaluated. As the results of antibacterial screening tests in vitro, quinoxaline 1, 4-dioxides revealed strong activities against Bacteroides fragilis.
