Syntheses of Amino Derivatives of Indole Series

Abstract

As ethylenediamine compounds of indole series assumed to possess antihistaminic properties, two kinds of N-(β-diethylaminoethyl)-α-methylindoles and four kinds of N-(β-diethylaminoethyl)-α-arylindoles were prepared by heating sodium salts of α-substituted indoles and β-diethylaminoethyl chloride in anhydrous toluene or xylene in the presence of sodium amide.