Chemical and Chemotherapeutical Studies on the Furan Derivatives. XVIII

Bacteriostatic Action of 2-(5-Nitro)-furanacrylic Acid Derivatives

Abstract

Eight kinds of naphthylamides, two kinds of naphthyl esters, and two kinds of phenyl esters, of 2-(5-nitro) furanacrylic acid derivatives were prepared and their antibacterial action were compared using Staphylococcus aureus, Streptococcus hemolyticus, and Shigella dysenteriae Komagome B III. 2-(5-Nitro) furanacryl-naphthylamide-(2), -4-chloronaphthylamide-(1), and -4-bromonaphthylamide-(1) showed powerful antibatcerial action against Strept. hemolyticus, but none of the substances examined were effective against Shigella dysenteriae.