Studies on the Metabolic Products of Penicillium islandicum Sopp. III

Abstract

Skyrin, iridoskyrin, islandicin, a pigment of m.p. 287° (decomp), and a pigment of m.p. 273° (decomp) were isolated from the ether extract of the mycelium of Penicillium islandicum Sopp, D strain. It is assumed that the pigment of m.p. 287° (decomp) is closely related in its chemical structure to the pigment of m.p. 273° (decomp), which has a toxicity LD₅₀ of 5mg./15g. mice (per os).