Effect of Nitrofurans on the Respiration of E. coli. I

Effect of Nitrofurans upon the Uptake of Phosphate

Abstract

Interference of malic oxidation of coil bacilli by nitrofurans (Furacin, Z-Furan, Guanofuracin) is not recovered by the addition of cystein or glutathione. Bacterial -SH group was determined after application of Guanofuracin to the bacterial suspension but its decrease was not detected. The absorption of inorganic phosphoric acid from the medium accompanying malic and succinic acid oxidation is detected on application of Furacin and Z-Furan but is almost entirely obstructed by Guanofuracin.