YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Application of Surface-Active Agents to Pharmaceutical Preparations. XIV. : Studies on the Temperature of Phase Inversion in the System emulsified with Nonionic Surfactants. (3) The Influence of Addition Components
Masaru AokiToichiro Matsuzaki
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JOURNAL FREE ACCESS

1967 Volume 87 Issue 7 Pages 765-768

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Abstract

Following the measurement of changes in electric resistance accompanying concentration changes in the emulsified system to make detailed analysis of inversion in that system by nonionic surfactants, effect of addition components on the temperature of phase inversion at the time of preparation of the emulsified system was examined. In the standard emulsified system consisting of nonionic surfactant, liquid paraffin, and water, changes in the temperature of phase inversion was measured on the addition of wax, higher fatty acid(s), and alcohol, ester as the oil phase component, and of polyhydric alcohols and salts as the water phase component. Changes in the nature of the system by changes in the compopents of the emulsified system, and nature of the additive substances can be expressed numerically, and these data were found to be useful in the preperation of an emulsified system.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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