YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Fundamental Studies on the Evaluation of the Crude Drugs. IV. Quantitative Analysis of Constituents in the Crude Drugs by Rod-Thin-Layer Chromatography with FID. (1). Determination of Glycyrrhizin in Liquorice Roots
TSUNEO NAMBAMASAO YOSHIZAKITSUYOSHI TOMIMORIMASAHIKO TSUBOIKIMIYO KATO
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1975 Volume 95 Issue 7 Pages 809-814

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Abstract

A new method for the determination of glycyrrhizin in liquorice roots was devised by the use of thin-layer chromatography over silica gel sintered rod with hydrogen flame ionization detector. It was found that glycyrrhizin was specifically absorbed on polyamide powder, and the test solution had to be prepared especially. Typical chromatograms obtained by this method are shown. Determination of glycyrrhizin in liquorice roots from China, Afghanistan, Iran, and U.S.S.R., and their processed goods on the Japanese market was made and the recovery rate was found to be more than 95% on the average.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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