The Study of Aqueous Extract of Puerariae Radix. IV. The Isolation of Daidzin from the Active Extract (MTF-101) and Its Antifebrile and Spasmolytic Effect

Abstract

From the aqueous extract (MTF-101) of Puerariae radix, daidzin (daidzein-7-glucoside) was isolated in 0.14% yield. The hypothermic effect of daidzin on rats and its spasmolytic effect on mice were examined in comparison with those of daidzein. Neither daidzin nor daidzein showed a hypothermic effect in a dose of 30 mg/kg s.c. on rats. Daidzein showed about 1/3 spasmolytic effect of papaverine on the small intestine of mice but daidzin showed no spasmolytic effect.