Prevalence of Eleven Infectious Viruses Causing Diarrhea in Korea

抄録

Rotavirus and norovirus are well-known causes of viral infectious diarrhea. There are few reports about diarrhea caused by other viruses in Korea, although gastroenteritis attributable to other viruses is increasing worldwide. The aims of this study were to detect various causes of viral diarrhea and to investigate their prevalence. A total of 801 fecal specimens submitted to a clinical microbiology laboratory for the detection of diarrhea viruses were included. We sought to detect rotavirus A/B/C, adenovirus, astrovirus, norovirus GI/GII, sapovirus, Aichi virus, human parechovirus, enterovirus, human cosavirus, human bocavirus, and Saffold virus using multiplex RT-PCR. At least one diarrhea virus was detected in 223 (27.8%) fecal specimens. Among them, two viruses were detected in each of 11 specimens. Rotavirus A was most common (17.1%; N=137), followed by norovirus GII (5.0%; N=40), enterovirus (4.2%; N=34), adenovirus (1.0%; N=8), astrovirus (1.0%; N=8), human parechovirus (0.6%; N=5), and human bocavirus (0.2%; N=2). Rotaviruses B and C, norovirus GI, sapovirus, Aichi virus, human cosavirus, and Saffold virus were not found. We confirmed that various diarrheal viruses can be detected in fecal specimens. We need to consider the possibility of viruses other than rotavirus and norovirus being present in cases of diarrhea.