1969 Volume 22 Issue 5 Pages 319-326
To find the distribution and the favourite site of localization of Toxoplasma in the cases of latent infection occurring naturally, the organs and other materials from 14 cats, 26 dye test-positive and 11 dye test-negative dogs were examined by inoculation into mice. Ten cats and 9 dogs were found to have been infected latently. In the cats, the organisms were isolated frequently from the diaphragm, brain, lungs, abdominal muscles, and heart muscles, and less frequently from the stomach, small and large intestines, mesenteric lymph nodes, spleen, and bile bladder. In the dogs, the parasites were demonstrated frequently in the diaphragm and abdominal muscles, and occasionally in the heart muscles, brain, small and large intestines, spleen, and uterus. The musculature particularly the diaphragm was found to be the most favourite site for the parasites in latently infected cases. A larger number of virulent strains killing mice within 1 or 2 weeks were found among the cat strains than among the dog strains.