フルオロビニル金属種を利用した含フッ素アルケン類の効率的合成

抄録

Fluorovinyl compounds like fluorostyrenes and fluoroacrylates have been drawing enormous interests as building blocks for various types of organofluorine compounds as well as monomers for high performance fluoropolymers. Although synthetic methods of fluorovinyl compounds have been developed since several decades, more effective and practical methods are still highly desirable. Reactions of organometallic species with electrophiles are recognized as one of the most effective and selective C-C bond forming reactions. The strategy could be adapted as the synthetic methods for various organofluorine compounds. Herein are described effective, selective and practical synthetic approaches to fluorovinyl compounds by employing fluorinated vinylmetal species, such as α,β,β-trifluorovinylmetal, α,β- and β,β-difluorovinylmetal, α- and β-fluorovinylmetal species.