石炭酸誘導体のカルボキシル化反応(第6報)

ニトロベンゼン中における石炭酸アルカリ塩よりパラオキシ安息香酸,サリチル酸の合成

抄録

Reactions between alkali phenoxides and carbon dioxide in nitrobenzene have been studied under various conditions.When potassium phenoxide was treated with carbon dioxide in nitrobenzene, salicylic acid was obtained in a good yield, whereas the formation of p-hydroxybenzoic acid was depressed as compared with similar reactions conducted in N, N-dimethylformamide. From sodiun phenoxide and carbon dioxide, salicylic acid was obtained as a main product, but p-hydroxybenzoic acid undetectable.Similar reaction was also carried out in nitrobenzene containing N, N-dimethylformamide. Though the yield of p-hydroxybenzoic acid was improved, the total yield of hydroxybenzoic acids was decreased.