1980 年 38 巻 11 号 p. 1092-1099
1 Discovery of 2-5 A
2.1.5 Methoxytetrahydopyranyl protection
2 Synthesis of 2-5 A
2.1.6 Metal catalyzed synthesis
2.1 Formation of 2'-5' internucletide linkages
2.2 Formation of 5'-triphsosphate (Synthesis of A 2' p 5' A 2' p5' A)
2. 2. 1 5'-Phosphorylation
2.1.1 Enzymatic synthesis
2.2.2 5'-Triphosphorylation with DCC
2.1.2 Chemical method using benzoyl protection2.2.3 Carbonylimidazolide method
2. 1. 3 o-Nitobenzyl protection
2.2. 4 Other methods
2. 1. 4 Silyl protection3 Biological activity of 2-5 A