Recent Trends in the Synthesis of Organofluorine Compounds

Abstract

The recent advances and trends in the synthesis of useful organofluorine compounds have been reviewed. This article is especially focused on the utility of commercially available fluorine-containing products as building block.Topics are discussed in the following four items : (1) introduction of fluoroalkyl groups in organic molecules using halofluorocarbons, (2) functionalization of fluorine-containing olefins, (3) ring-opening reaction of fluorocyclopropanes to give fluorobutadienes or ketones, and (4) carbon-carbon bond forming reaction of fluorine-containing carbonyl compounds.