有機モノフルオロ化合物合成のための合成ブロック

抄録

The methodologies employed in the use of building blocks in the synthesis of various kinds of monofluoro molecules are reviewed in light of recent increasing interest and demand for organofluorine compounds in synthetic and biological chemistry. The building blocks were chosen with the following two criteria in mind : ease of preparation or commercial availability and wide applicability of the compounds derived therefrom.
This article is organized into four sections : i) the necessity of and requirement for building blocks, ii) the building blocks for the preparation of various kinds of vinyl fluorides, iii) the building blocks for the preparation of various kinds of alkyl fluorides, and iv) versatile and practical building blocks with wide synthetic applicability.