有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
企業の製品安全担当者から見たいわゆる環境ホルモン問題
西川 洋三
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1999 年 57 巻 1 号 p. 53-57

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Some exogenous chemicals such as PCB, tributyltin compounds (TBT), and diethylstilbestrol (DES) are reported to disrupt the action of the sex hormones, thus resulting in unexpected biological effects. The manufacture and use of these chemicals have strictly been restricted in Japan. Bisphenol A and nonylphenol are suspected to be endocrine disrupter. However the both phenol chemicals are degradable in the environment and far less toxic than PCB, TBT and DES.
Environmental pollution with chemical substances are reported to be getting serious every year by mass media. However it peaked around 1970 and has been improved evidently since that. This report deals with the overall evaluation of the endocrine issue in Japan.

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