Since 1982, 4-META/MMA-TBB resin cement (Superbond, Sun Medical, Moriyama, Shiga, Japan; SB) has been applied to preserve root fractures (RFs) in 317 patients (369 roots) treated in our clinic from February 1982 to December 2016, respecting patients’ wishes. Follow-up data were collected as of December 31, 2021. The 5- and 10-year survival rates were 92.7% and 65.9%, respectively, with a median survival time of 15.08 years. A multivariate Cox hazard model identified patient age and Masaka’s classification (Type M-1: U-shaped RFs treated by intraoral adhesion method) as significant prognostic factors. The hazard ratio for age was 1.022 (95% CI: 1.008–1.037). Type M-1 cases showed a 10-year survival rate of 94.7% with more than half of the treated teeth remaining functional at the time of data collection. These findings suggest that SB can effectively restore and maintain the function of RFs for a decent period.

Bone defects of oral and maxillofacial have always been the difficult problems in clinical treatment. Traditional methods like autografts or allografts bone graft still remain some disadvantages. With the developments of bone tissue engineering, the applications of marine organisms have attracted lots of attention. This research intended to prepare a synergistic pepsin-hydrolyzed tilapia fish collagen (PHFC)/hydroxyapatite (HAP) composite, which based on the components and structure of natural bone extracellular matrix (ECM). Through in vitro and in vivo experiments, we preliminarily demonstrated that this composite exhibits excellent biocompatibility, appropriate degradation rate, and favorable osteogenic properties. In conclusion, this novel material can be regarded as bioactive ingredient for biomaterials used in bone regeneration.

In this experiment, calcium salt (MDP-Ca) was synthesized from methacryloyloxydecyl dihydrogen phosphate (MDP), which is an adhesive monomer, and blended into a bonding system (Hybrid Coat: HC). The results from the microtensile and the indentation hardness revealed that HC with 1.50% MDP-Ca (MDCP) had higher values. In the FE-SEM observations, MDCP began to change its structure with a dense etching pattern after 24 h of immersion earlier than HC. These results indicated that MDP-Ca strengthened the mechanical structure of the hybrid layer because the initial bonding strength and indentation hardness of MDCP were greater than those of HC. Then MDCP was observed to have a dense structure that was resistant to ion etching treatment within 24 h. Thus, the addition of an appropriate concentration of MDP-Ca improved the initial bonding strength and mechanical properties of the prototype bonding material and formed a hybrid layer that was useful as a coating material.

This study investigates the correlation between Amide I and III components in dentine’s infrared spectrum, focusing on structural changes due to acidic conditioning and adhesive treatments. Human dentine specimens (n=40) were treated with phosphoric acid, phytic acid, and two self-etching adhesives (G-Premio Bond and Adhese Universal), then analyzed using ATR-FTIR spectroscopy. Deconvolution of Amide I and III peaks quantified changes in secondary structures, including α-helices, β-sheets, and β-turns. Results showed strong positive correlations between specific Amide I and III components. The collagen triple helix remained stable after treatment, indicating its potential for normalizing Amide III components. Amide I, however, remains preferred for calculating the mineral-to-matrix ratio due to its higher intensity. The study highlights that Amide III analysis may be more accurate for monitoring structural changes in dentine collagen, avoiding errors from overlapping water vibrations with Amide I.

This study evaluated the shear bond strength (SBS) between cobalt-chromium (CoCr) and titanium (Ti) alloys fabricated via selective laser melting (SLM) and denture base resins with different bonding methods. After surface pretreatment of cylindrical CoCr and Ti alloy specimens, bonding was performed using three methods: the compression molding (CM) method, the pouring (PT) method, and the method using 4-META/MMA-TBB resin (SB). SBS tests were performed after storing all specimens in distilled water at 37ºC for 24 h, either immediately or following 10,000 thermocycles. For CoCr alloys, without thermocycling, the CM method exhibited significantly higher SBS than SB method (p<0.001), but no significant differences were observed with thermocycling. For Ti alloys, the CM method showed significantly higher SBS than the SB method without thermocycling (p=0.018) and was higher than the PT method with thermocycling (p=0.047). These results suggested the CM method may be a promising bonding technique for SLM-fabricated alloys.

This study aimed to evaluate the effect of various surface treatments of a fiber post on the bond strength to a composite core. The polished flat surfaces of fiber posts received different treatments: C (no surface treatment), S (silanization only), HS (30% hydrogen peroxide etching followed by silanization), HNS (etching with a 30% hydrogen peroxide/5 wt% sodium bicarbonate mixture followed by silanization), and SBS (sandblasting and then silanization). Resin composite cylinders were bonded on each pretreated surface and all bonded samples were stored in water at 37ºC for 24 h, with half of them additionally thermocycled for 10,000 cycles before microshear testing. Surface morphology and elemental composition of the conditioned post surfaces were studied by scanning electron microscopy and energy dispersive X-ray spectroscopy. The HNS exhibited the highest bond strength, regardless of thermocycling (p<0.05). Although etching and sandblasting increased surface roughness, sandblasting caused structural damage of the post.

Calcium phosphate (CaP) bioceramics, including apatite (Ap)-based materials, are naturally biocompatible, but they frequently require surface functionalization to achieve optimal integration with biological systems, especially with immune cells. Surface functionalization strategies tailor CaP bioceramic nanoparticles to enhance cell adhesion, proliferation, differentiation, and overall biocompatibility. This is because functionalized surfaces interact more dynamically with immune cells, i.e., macrophages, dendritic cells, and lymphocytes, through surface receptors and signaling pathways. The dynamic interaction may activate immune cells, release cytokine, differentiate cells, and regulate inflammation. Therefore, to resolve the limitations of natural CaP bioceramics, surface functionalization is crucial. Modified bioceramics nanoparticles’ surface properties ensure more effective integration with biological tissues. In addition, biomolecule immobilization on CaP bioceramic surfaces provides a versatile approach in establishing a foundation for the development of immunomodulatory biomaterials. This review provides an overview of recent biomedical research on CaP bioceramics, especially Ap-based materials, focusing on advancements in surface functionalization strategies designed to improve interactions with immune cells. It also examines the role of immobilized biomolecules in modulating immune responses, highlighting their potential for clinical applications.

Polyetheretherketone (PEEK) cannot be used without veneering in the anterior area. This study aims to observe the influence of the various surface treatment protocols on the shear bond strength (SBS) between veneering resin composite and PEEK. Sixty cylindrical PEEK specimens (16×5 mm) were fabricated using CAD-CAM, and divided into six groups (n=10) based on the surface treatment method: NT: no treatment (control), SA: 98% sulphuric acid, HP: 30% hydrogen peroxide, SB: airborne particle abrasion with 50 µ aluminum oxide particles, SL: silicatization followed by silanization, and HF: 9.5% hydrofluoric acid. After the application of the resin composite, specimens were thermocycled and subjected to fracture testing using a universal testing machine. Fractured surfaces were examined microscopically and the data were analyzed statistically. The SA and SL groups exhibited significantly higher mean SBS values (p<0.001), although the difference between them was not statistically significant (p=0.24).

This study aimed to evaluate the conditions for the finish line position and gingival retraction width that allow for taking optical impressions using three-dimensional (3D) printed models. Taking an impression using an intraoral scanner (IOS) is widely performed in fabricating crown prostheses. Measuring the subgingival finish line using an IOS is difficult; to obtain optical impressions of the subgingival finish line, the gingival retraction has been recommended. However, no study has evaluated the amount of gingival retraction width and the depth of the finish line. In this study, the measurement limits of the subgingival finish line using an IOS and models fabricated by a 3D printer were investigated. The results of this study revealed that TRIOS3 could not measure the finish line when the gingival retraction width was <0.25 mm, and the finish line was located >0.50 mm below the gingival margin.

The objective of this study was to evaluate polyetheretherketone (PEEK) as a post material for resin core abutments in bovine root by static and dynamic fracture loads, with comparison for fiber-reinforced composite (FRC) post. Resin core abutments using experimental PEEK post (CR-PEEK) and bovine root (BRA-PEEK) were fabricated. Specimens including those built-up FRC posts instead of PEEK posts (CR-FRC and BRA-FRC) were also evaluated for load durability under static and dynamic loading tests. CR-PEEK had a lower fracture load than CR-FRC. BRA-PEEK and BRA-FRC had similar static and dynamic loads, with the primary fracture mode involving delamination of the abutment from the tooth structure due to ferrule fracture, with plastic deformation in the experimental PEEK post. In conclusion, experimental PEEK post could be a viable post material for resin core abutment when used in combination with resin composite.

This study investigated the impact of 1,500 ppm fluoride-containing toothpaste on the surface properties of CAD-CAM resin composites. An accelerated degradation test was performed using five commercial NaF-containing toothpastes, which were applied to two commercial CAD-CAM resin composites and stored under static conditions at 37°C for 14 days without mechanical brushing. The results showed that four toothpastes significantly increased surface roughness and reduced gloss. To further elucidate this phenomenon, a similar accelerated degradation test was conducted using experimental aqueous solutions containing NaF (1,500 ppm) and sodium dodecyl sulfate (SDS; 2 wt%), a common component in the toothpastes that caused the most severe degradation. The findings indicated that SDS accelerates the degradation of CAD-CAM resin composites in the presence of NaF, suggesting that toothpastes containing both NaF and SDS contribute to the deterioration of surface properties.