A case of a 60-year-old right-handed male patient with alexia with agraphia due to cerebral infarction was presented here. A CT scan and MRI of the brain revealed that a lesion was present in the left white matter and area of perforating arteries. On admission he showed difficulty in word finding and auditory comprehension, but one month later, these aphasic symptoms improved. The patient's chief complaint was his inability to read and write. Reading of Kana was more severely impaired than that of Kanji, but his reading significantly improved after 3 months. On the contrary, agraphia of Kana and Kanji remained. Substitutional errors were present in Kana writing, but not in Kanji writing. He showed difficulty in recalling the visual image of the target letter. A home practice program to improve his writing was devloped. The materials for this program consisted of pictures, a printed short sentences to describe the picture, and a tape recording of the sentence. The patient was instructed to look at the picture and the short sentence while listening to the tape, and to remember all of the sentence. During speech therapy, he was asked to recall the sentence and to write it. This traning proved to be effective in improving his agraphia. This suggested that the home therapy progrom activated neural pathways for recollection ability.
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