The aim of this study was to examine the social benefits of different treatment options for patients with epilepsy and their families. We evaluated the willingness to pay (WTP) of patients and their families and analyzed factors related to WTP for two treatment options: 1) continue current therapy and 2) switch to new therapy that can achieve ideal condition without seizures. A web survey was conducted, and a total of 932 valid responses were obtained from patients receiving antiepileptic drugs and their families. The results showed that, with an acceptance rate of 50%, the WTP of option 1 was 1,448 yen/month in addition to current self-payment while that of option 2 was 3,791 yen/month in addition to current self-payment, and the difference between the two options was 2,343 yen/month. Factors affecting WTP include type of respondents (families), employment status of patients, household income, and the frequency of the most severe seizures. The results of this study confirmed that social benefits of epilepsy treatment were greatly influenced not only by seizures but also by living environment.
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