In an attempt to clarify the clinico-electroencephalographical characteristics of the epilepsy with continuous spike-waves during slow wave sleep (ECSWS). I inves tigated the 29 patients whose spike-wave index (SWI) during sleep exceeded 25%, and the patients were classified into the following 3 groups; Group I (SWI: 85%) Group II (SWI: 50-84%), and Group III (SWI: 25-49%).
The results are as follows:
1) The age of onset and disappearance of continuous spike-waves during slow wave sleep (CSWS) ranged from 3 to 15 years old, but no significant difference among the 3 groups was noticed. The average duration of CSWS was found significantly shorter in Group II and III than Group I.
2) The epileptic seizures observed in complication with ECSWS became disappeared by the age of 15 years old, and there was no case leading to an adult intractable epilepsy.
3) Permanent mental defect was observed for the patients whose SWI exceeded 50%, particularly all the patients of the Group I revealed mental deterioration. Mental deterioration was also observed for all the patients whose CSWS continued for more than 2 years.
4) In the International Classification of Epilepsy, ECSWS is classified as undeter mined epilepsy. However, we pointed out that ECSWS shares many of the factors with localization-related epilepsy.
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