Non-invasive tissue oxygenation monitoring system based on Near-InfraRed Spectroscopy (NIRS) is expected to be used in the various applications such as medical field and brain studies. We have developed the new instrument which incorporates the wireless communication system so that unconstrained measurements can be done. The instrument consists of 3 different wavelengths LEDs as light sources and one photo-diode as a detector. The measured data were sent to personal computer through wireless communication system up to 60 data per second. We demonstrated that the system could monitor the high-speed sampling measurement of the hemoglobin concentration change in an unconstraint subject. We found the pulsation of measurement data in the hemoglobin concentration change due to heart beat. These results indicate that the NIRS technology system can evaluate blood circulation by local oxygen metabolism information and a pulse rate measurement that reflects general circulation at the same time. This NIRS system can be used as the oxygenation monitor not only for existing medical applications but also for new applications.

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