The Journal of Japanese Society of Limb Salvage and Podiatric Medicine
Online ISSN : 2187-1957
Print ISSN : 1883-857X
ISSN-L : 1883-857X
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Volume 2, Issue 2
Displaying 1-14 of 14 articles from this issue
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Opening Article
Review Articles
Our Address to Limb Salvage
Case Report
  • [in Japanese], [in Japanese], [in Japanese]
    2010 Volume 2 Issue 2 Pages 153-158
    Published: 2010
    Released on J-STAGE: March 27, 2015
    DOIhttps://doi.org/10.7792/jlspm.2.153
    JOURNAL RESTRICTED ACCESS
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    Here a patient, a 78-year-old woman, with progressive toe necrosis and local severe pain due to collagen disease was presented. The case showed no reaction with various treatments on the guideline for vascular lesions combined with collagen disease. Then oral administration of sildenafil was indicated and significantly suppressed the local severe pain and progress of the necrosis. Then the leg and foot was preserved, and the patient could depart on foot from the hospital. It is suggested that sildenafil is effective for refractory cases due to vascular lesions of collagen diseases. However, although public indication of sildenafil is fixed in pulmonary hypertension, in this time the application for the patient without the sign is currently off-label use. Therefore, the administration should be limited to refractory patients to conventional therapies. Sufficient informed consent should be established. Medical stuffs should pay great attention to the patient during the treatment.
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