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Volume 35 (1993)
- Issue 6 Pages 449-
- Issue 5 Pages 371-
- Issue 4 Pages 297-
- Issue 3 Pages 221-
- Issue 2 Pages 115-
- Issue 1 Pages 1-
Predecessor
Volume 35, Issue 3
Displaying 1-6 of 6 articles from this issue
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Hidenori Kaminishi, Tamaki Cho, Toshiko Sakima, Yoshisato Hagihara, At ...1993 Volume 35 Issue 3 Pages 221-226
Published: June 20, 1993
Released on J-STAGE: October 28, 2010
JOURNAL FREE ACCESSSecretory proteinase from Candida albicans was studied for its ability to activate plasma clotting. The experiments were carried out by using the proteinase with normal plasma, Hageman factor deficient plasma and Factor X deficient plasma. When each plasma was treated with the proteinase, the thrombin activity occured in the normal plasma as well as in the Hageman factor deficient plasma and Factor X deficient plasma. Moreover, in experiments using purified Factor II and Factor X and Factor XII, the proteinase converted all factors in a way that allowed it to initiate the clotting cascade. The evidence suggests that the activation of each plasma and each factor by C. albicans proteinase is due to a limited proteolysis of Hageman factor, Factor II, and Factor X. Conversion of each factor except Factor IX to the active form, and the generation of thrombin in each plasma by the proteinase were observed at a pH range between 4.5 to 6.0. The result indicates that Candida proteinase has the potential to activate the blood clotting system and aggravate the infection process.View full abstractDownload PDF (922K) -
Initial calcification processes inside the pores of porous hydroxyapatite ceramics implanted in the submandibular glands of ratsTetsuo Morimitsu, Hiroshi Inoue, Tsukasa Nakamura, Keiji Watanabe, Ets ...1993 Volume 35 Issue 3 Pages 227-236
Published: June 20, 1993
Released on J-STAGE: October 28, 2010
JOURNAL FREE ACCESSThe initial calcification processes inside the po res of porous hydroxyapatite ceramics implanted into the submandibular salivary glands of rats were observed by light -microscopy and by scanning and transmission electron-microscopy at varying int ervals for 10 weeks after implantation.The inorgani c elements inside the pores were examined by line- and surface-analysis with x-ray-d etection energy-dispersive analysis.
The porous hydroxyapatite ceramics were encapsulated with a layer of fibrous tissue during the later stages, although during the earlier stages the surr ounding tissues showed inflammatory phenomena.Insid e the pores of the implants, two types of calcification processes were observed. The first type was devoid of cells or any collagen fibrils, whereas in the second type, fibroblast-like cells, whichi nvaded the pores of the implants, and collagen fibrils appeared to be associated with the initial calcification processes.View full abstractDownload PDF (8586K) -
Primary structure and immunohistochemical localization of dog osteocalcinOsamu Nakade, Tohru Kaku, Toshikatsu Matsuyama1993 Volume 35 Issue 3 Pages 237-250
Published: June 20, 1993
Released on J-STAGE: October 28, 2010
JOURNAL FREE ACCESSWe determined the complete amino-acid sequence of dog osteocalcin and cultured the antibody against it. We also examined the immunohistochemical localization of osteocalcin on dog bones.
Dog osteocalcin consisted of 49 amino acid residues (MW: 5, 682), and the complete sequence was determined to be YLDSGLGAPVPYPDPLXPKRXVCXLNPNCDELADHIGFQEAYRRFYGPV (X=Gla). Although Serine-4 is unique to dog osteocalcin, a high homology was seen between the osteocalcin from dogs and that from other mammals.
Osteocalcin immunoreactivity was detected in osteoblasts, osteocytes and some preosteoblasts. In osteoclasts, both positively and negatively stained cells were observed. However, fibroblasts and chondrocytes were not stained positively.
These results should prove useful in various bone metabolic studies using dogs as an experimental animal.View full abstractDownload PDF (5635K) -
Deposits of various metallic dusts observed at autopsy in a dental health care worker with lung cancerTetsunari Nishikawa, Sayoko Ohmori, Masahiro Wato, Jun Tsutsui, Yasuno ...1993 Volume 35 Issue 3 Pages 251-254
Published: June 20, 1993
Released on J-STAGE: October 28, 2010
JOURNAL FREE ACCESSDownload PDF (1978K) -
Effect of sialoadenectomy on epidermal growth factor concentration in serum and urine of miceFumitoshi Takayama, Masahiko Hiramatsu, Masanori Kashimata, Naomi Mina ...1993 Volume 35 Issue 3 Pages 255-258
Published: June 20, 1993
Released on J-STAGE: October 28, 2010
JOURNAL FREE ACCESSDownload PDF (595K) -
Effects of hypophysectomy and subsequent administrations of testosterone, triiodothyronine, and growth hormone on epidermal growth factor concentration in rat submandibular glandFumitoshi Takayama, Masahiko Hiramatsu, Masanori Kashimata, Naomi Mina ...1993 Volume 35 Issue 3 Pages 259-262
Published: June 20, 1993
Released on J-STAGE: October 28, 2010
JOURNAL FREE ACCESSDownload PDF (591K)
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