Appropriate instruction to patients by medical staff is essential for the proper use of insulin-containing products. In 2020, the package insert “Important Precautions” for insulin-containing products included a warning of subcutaneous induration caused by insulin injection. This study conducted a survey of pharmacists belonging to the Federation of Diabetes Educators in Hyogo to ascertain their current knowledge and teaching methods regarding subcutaneous induration. Questions included knowledge, instruction, prevention, and patient awareness regarding subcutaneous induration. We found that hospital pharmacists were generally more knowledgeable than community pharmacists with regards to subcutaneous induration. Moreover, in teaching patients how to inject insulin, about half of the community pharmacists did not check the patient’s injection site. Because only 11 out of 21 of hospital pharmacists and 7 out of 24 of community pharmacists answered that they knew the addition of a warning about subcutaneous induration to the package inserts of insulin-containing products, awareness was found to be lacking. Pharmacists are required to contribute to safer and securer medication therapy by providing proper knowledge and skills, including subcutaneous induration, for patients who self-inject insulin.