Les auteurs ont essayé d'expérimenter si le tissu testiculaire du lapin peut permettre de multiplier le virus variolique comme celui de la vaccine et de le transformer en vaccine.
Comme matière d'expérience, les auteurs ont recueilli des croutes sur 6 varioleux. Avec ces croûtes, ils ont preparé 6 émulsions distinctes, diluées IO fois d'eau glycérinée. Ces émulsions ainsi préparées ont été toutes inoculées à la peau de l'abdomen d'un singe pour comparer la virulence des èmulsions et choisir la matière d'expérience convenable. Au bout de quelques jours, des inoculations de l'une des émulsions ont produit des très belles pustules; mais les autres n'ont produit que des vésicules plus on moins incomplètes. Les auteurs ont donc pris l'émulsion la plus active pour faire leur expériences.
Des inoculations de cette émulsion ont été pratiquées sur diverses parties du corps d'un lapin: à la cornée (par la, scarification), aux muqueuses labiales et nasales (par les scarifications), à la peau rassée du dos (par les frottements de pointe rugueuse d'une pipette chargée d'émulsion), et enfin, en même temps, on a injeté I cc de l'émulsion à l'un des testicules de cet animal.
A la cornée, une légère tuméfaction s'est tout simplement manifestée; mais elle a bientôt disparu; aux muqueuses et à la peau, on n'a observé aucune altération nosologique; tandis que, au testicule, l'injection a provoque une inflammation hémorrhagique assez remarquable.

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The author determined the resistance of the red blood-corpuscles against hypotonic solutions of sodium chlorid in 12 experimentally infected cases of “infectious anemia of horses.” The method employed by the author is in principle similar to that of Hamburger. It only differs from the latter in the point that the mixture of blood-corpuscles and salt solutions remains for one hour in a thermostat and for 20 hours in an icechamber. The results obtained from the author's experiments are as follows:
1) In 30 conrol horses the maximum-and minimum-resistance of the red blood-corpuscles is on an average as high as 0, 45 g/dl and 0, 54 g/dl of salt solution respectively. In 12 infected horses the author demonstrated a distinct diminution of the resistance, i. e. the maximumand minimum-resistance lies in these cases at 0, 51 g/dl and 0, 59 g/dl respectively. There is, however, in these cases, showing diminished resistance, no distinct relationship between the grade of the anemia (oligocytaemia) and the diminution of the resistance.
2) The maximum-and minimum-resistance diminishes in infected horses almost equally, so that the amplitude of the resistance (Resistenzbreite) remained unaltered from that in normal horses. The author therefore, comes to the conclusion that the red blood-corpuscles of the infected horses must be subject to an uniform diminution of resistance.

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1) The author made a thorough study of one of the epidemics of typhus, which occurred in Aomori-Prefecture in 1918. In this epidemic there were 48 cases in eighteen families. In none of these cases was the origin of infection obscure. The infection occurred in only three ways: (a) by coming near the patient or visiting the patient's family, or (b) by approaching the corpse of a typhus case, or (c) by touching things or persons, which had formerly come in contact with the patient or the corpse. In other words there was not a single case of typhus, which had not some relation with a former case of typhus, directly or indirectly.
2) When a patient in a family is not isolated in proper time and manner and the house is not sufficiently disinfected it usually happens that most of the other members of the family are infected with typhus, not simultaneously, but one after another in a more or less long period of time.
3) The causative agent of typhus does not usually remain infectious, when separated for some time from the patient. But the author has strong evidence, that the disease may be transmitted to man by means of something or somebody, free from typhus, carrying the virus.
4) From a relatively, early stage of the disease, most of the patients show some signs of bronchitis and complain of cough.
5) Lice are abundantly present in the clothes of the patient. It is believed that while the patient is living, these lice do not so easily detach themselves from their host, but on the contrary, very rapidly leave, when the patient is dead, and attack another, healthy, person.
6) It is a very interesting fact that the time of incubation distinctly varies according to the mode of infection. Those who are infected by close contact with the patient, show an incubation period of 7 days on an average. Those infected by coming near the corpse of a typhus, case or by other indirect means, show a relatively long time of incubation, i. e. 17-18 days on an average. The author therefore considers, that the infection occurs in the former case very often by the socalled droplet infection and in the latter case mostly by means of the louse.

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The author made a statistical study of typhoid cases, treated in the Komagome Municipal Hospital, Tokyo. Out of 222 cases the typical and the remitting type of fever were found in almost the same number. From the prognostic viewpoint those with non-remitting fever appear to be severer than the other.
Concerning the stools of 313 typhoid cases 74% of cases had more or less marked constipation and the remaining complain usually. of diarrhoea. In the latter cases the illness is often severer and the intestinal haemorrhage is more frequent in these.

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The authors made a bacteriological study of the throat secretion of the doctors and nurses in the U.S.A. Red-Cross-Hospital and of the American soldiers, who were supposed to have been in connection with a patient suffering from cerebrospinal meningitis.
As there was an epidemic of Spanish fever at that time in Vladivostok and most of the examined persons were said to have had it, the authors tried to cultivate both the meningococcus and influenza bacillus. For determination of the meningococcus they applied the agglutination test and Lingersheim's culture media, Pfeiffer's bacillus, on the other hand, was determined by cultural and morphological properties. Out of 214 persons 42 (19, 6%) were found to be meningococcus carriers and among 194 examined 30 (15, 5%) proved to be carriers of Pfeiffer's bacillus.
The fact deserving emphasis is, that a discrepancy between the agglutination and fermentation test is rarely observed as to the meningococcus; the strains from 4. cases, which showed positive agglutination reaction, had no fermentative power at all, while in 5 other cases just the reverse was found.

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