[purpose] The medicinal solution leak of the injection medicine from the connection part of a syringe and the infusion solution tube has a serious influence on a patient. However, the leaked medicinal solution was not discovered easily by watching for small amount and transparency.I developed the medicinal solution leak detection paper (the following, the detection paper) that can detect medicinal solution leak by this time-colored fading, and performed the clinical use.
[method] The thin paper that had soaked the ascorbic acid and the thin paper that had soaked the povidone iodine were made, and they were dried. These were overlapped, bound, and the detection paper was made.
[result] Developed detection paper started fading with the quantity of liquid of 0.1mL in 10 seconds, and the sensitivity of fading was good.
[Consideration] When the medicinal solution which leaked soaks into the detection paper, a color of the povidone iodine fades.This used the reaction that a color of the povidone iodine faded by the reduction action of the ascorbic acid.I could know medicinal solution leak by this fading and am easy to have come to make discovery by the watching.
The color of the detection paper has discolored to the experiment that soaks 4% acetic acid liquid having the oxidation action into the detection paper.From this experiment result, I think the detection paper to be have fading reaction for medicinal solution leak of clinical used injection medicine.
The developed detection paper was possible to make handily and cheap by using a safe medicine and the material, and even clinical use was useful.
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